pharmacology heamostasis and thrombosis
pharmacology heamostasis and thrombosis
- Created by: james pratt
- Created on: 08-12-11 07:27
Other questions in this quiz
2. thrombosis which is false
- arterial thrombi: mainly of platlets and WCC normally the result of endothelial damage
- venous thrombi tend to consist of platlets, WBC and RBC
- defined as the pathological formation of a clot in the absence bleeding
- venous thrombi can cause DVT and PE
- thrombus formation is predisposed by injury to vessel wall, altered blood flow abnormal coagulability
3. which is true of thrombotic drug therapy
- anticoagulants increase blood coagulation
- antiplatlet drugs alter platlet function
- drugs normally prevent haemostasis not thrombosis
- fribrinolytics break down platlets
4. which is false of the coagulation cascade
- intrinsic for clotting of shed blood
- the two pathwyas do not converge
- intrinsic and extrinsic pathways involved in the cascade
- extrinisic for in vivo
5. false of the coagulation cascade
- inactive precursors are activated by proteolysis
- VIIa can act on factor X to produce factor Xa
- the binding of tissue factor VII in the presence of Ca converts VII to VIIa
- each inactive factor then cleaves the next inactive factor
- blood contains the necessary components for coagulation in the inactive form
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