Pharmacology - Pharmacokinetics

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  • Created by: Eltanova
  • Created on: 27-09-20 20:44

1. What is the definition of bioavailability?

  • Process of albumin attachment, which does not allow for glomerular filtration in renal excretion
  • Duration taken for drug concentration to fall to half its original concentration
  • Proportion of drug administered that reaches systemic circulation
  • Metabolism by conjugation reactions, enabling prolonged stay of drugs in body
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2. Which of the following is: The percentage of administered drug that reaches systemic circulation

  • Steady State
  • (AUC Oral / AUC IV) x 100
  • Half life
  • Loading dose

3. Which of the following is: Initially giving a patient a large dose, which is then adjusted with treatment

  • Steady State
  • (AUC Oral / AUC IV) x 100
  • Loading dose
  • Half life

4. Which of the following is not a route of administration of a drug?

  • Buccal
  • Intranasal
  • Percutaneous
  • Sublingual
  • Excretion
  • Inhalation
  • Oral
  • Intramuscular
  • Rectal
  • Intravenous
  • Subcutaneous
  • Transdermal

5. Why do drugs concentrate in breast milk?

  • Drugs do not readily concentrate in breast milk
  • None of the above
  • More acidic than plasma
  • Ion releasing phenomena
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