Monoclonal Antibodies 0.0 / 5 ? BiologyMicrobiology and fungiBiological molecules, organic chemistry and biochemistryCellular processesCellular processes and structureHuman, animal and plant physiologyHealth, illness and diseaseImmunityVaccinationASAQA Created by: Betsy_2018Created on: 04-01-17 20:52 What is the basis of Monoclonal Antibody Therapy (MCAT)? Some cancers have specific proteins on their outsides; humoral, active immunity 1 of 8 How does Monoclonal Antibody Therapy treat cancer? Bind to specific (cancerous) antigens and destroy the cell; block chemical signals that stimulate uncontrolled growth 2 of 8 Why is MCAT unethical? Induced mice with cancer, causing tumours and death 3 of 8 Why is informed consent needed for testing and treatment of MCAT? Because sometimes organ failure occurs due to overproduced immune response stimulants or attacked tissues 4 of 8 Why can prostate cancer be seen in the early stages using MCAs? Specific protein produced (Prostate Specific Antigen) in high levels; early warning sign; look for antigen-antibody complexes 5 of 8 Why can breast cancer be treated using MCAT? Breast cancer produces specific antigens; Herceptin drugs can be used; non-toxic, highly specific antibodies can target it 6 of 8 What is Indirect Monoclonal Antibody Therapy? A radioactive/cytotoxic drug is attached to antibody; small doses are cheaper and less dangerous; destroy cells, including cancer cells 7 of 8 Why can monoclonal antibodies be used for pregnancy testing? Placenta produces hCG glycoprotein; hCG-antibody-colour complexes formed in urine sample; colour line along ***** until caught by another antibody 8 of 8
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