Mitosis/DNA replication Q&A

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Describe what happens during metaphase (2)
Spindle formed / chromosome/centromere/chromatids attaches to spindle; Chromosomes/chromatids line up/move to middle/equator (of cell);
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Describe what happens during anaphase (2)
Chromosome/centromere splits / chromatids/ ‘chromosomes’ separate/pulled apart; To (opposite) sides/poles/centrioles (of cell);
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Cells lining the human intestine complete the cell cycle in a short time. Explain the advantage of these cells completing the cell cycle in a short time. (1)
Form/replace cells quickly/rapidly / divide/multiply/replicate rapidly;
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Mikanolide is a drug that inhibits the enzyme DNA polymerase. Explain why this drug may be effective against some types of cancer (2)
Mikanolide is a drug that inhibits the enzyme DNA polymerase. Explain why this drug may be effective against some types of cancer
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Mitosis is important in the life of an organism. Give two reasons why.(2)
1. Growth / increase in cell number; 2. Replace cells / repair tissue / organs /body; 3. Genetically identical cells; 4. Asexual reproduction /cloning
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Describe how DNA is replicated. (6)
Strands separate / H-bonds break; 2. DNA helicase (involved); 3. Both strands/each strand act(s) as (a) template(s); 4. (Free) nucleotides attach; 5. Complementary/specific base pairing / AT and GC; 6. DNA polymerase joins nucleotides (on new
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Describe the role of the centromere in mitosis (2)
1. Holds chromatids together; 2. Attaches (chromatids) to spindle; 3. (Allows) chromatids to be separated/move to (opposite) poles / (centromere) divides/splits at metaphase/ anaphase;
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DNA helicase is important in DNA replication. Explain why (2)
Separates/unwinds/unzips strands/helix / breaks H-bonds; 2. (So) nucleotides can attach/are attracted / strands can act as templates;
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Card 2

Front

Describe what happens during anaphase (2)

Back

Chromosome/centromere splits / chromatids/ ‘chromosomes’ separate/pulled apart; To (opposite) sides/poles/centrioles (of cell);

Card 3

Front

Cells lining the human intestine complete the cell cycle in a short time. Explain the advantage of these cells completing the cell cycle in a short time. (1)

Back

Preview of the front of card 3

Card 4

Front

Mikanolide is a drug that inhibits the enzyme DNA polymerase. Explain why this drug may be effective against some types of cancer (2)

Back

Preview of the front of card 4

Card 5

Front

Mitosis is important in the life of an organism. Give two reasons why.(2)

Back

Preview of the front of card 5
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