Microbiology lecture 10

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Wha are the symptoms of vibrio cholera?
Rice water diarrhoea
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What is the virulent factor of vibrio cholera?
cholera toxin (AB type)
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What is the toxin of vibrio cholera encoded on?
phage genome (CTX)
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What is the treatment for vibrio cholera?
Liquid and electrolyte replacement
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What does bacteremia?
Bacteria in the blood
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What is septicaemia?
blood borne systemic infection
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Whats is septic shock?
Inflammatory response to bacteria in blood stream
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What are two opportunistic pathogens?
streptococcus and staphylococcus
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What 2 diseases does S.enterica cause?
1) Enterocolitics (gastroenteritus) - a localised infection 2) Enteric fever (typhoid fever) - a systemic infection
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Streptococcus: Grame +ve/-ve, shape?
Gram +ve, cocci and grows in chains. Can be capsulated
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Where are Streptococcus infection sites?
Throat, middle ear, mammary glands, skin, lungs
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What are Streptococcus diseases?
Pharyngitis, Scarlet fever, Streptococcal toxic shock syndrome, pneumonia
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Staphylococcus: Gram +ve/-ve, shape?
Gram +ve, cocci, grape-like clusters
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What are Staphylococcus diseases?
Pimples, Impetigo, toxic shock syndrome, pneumonia, meningitis, septicaemia
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What is pneumonia?
Secondary infection, inflammation of the lung parenchyma
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What are the majority strains of MRSA resistant to? And how is it obtained?
Methicillin. Horizontal gene transfer --> mecAWher
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Where does M.tuberculosis grow?
Inside activated macrophages - exploits bodies own immune system
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What does L.pneumophila cause?
Mild cough, headache, fever, develops into pneumonia
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H.pylori: Gram +ve/-ve, shape?
Gram -ve, motile and spiral shaped
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What does H.pylori cause?
Gastritis, Gastric ulcers, gastric cancers. May individuals are asymptomatic carriers
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What does Uropathogenic E.coli cause?
Pyelonephritis, Acute cystitis
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What are the 2 types of uropathogenic E.coli?
1) Cystisis - type 1 pilus (fim genes) 2) Pylenophrytis (pap genes)
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What is the major virulence factor of uropathogenic E.coli?
fimbriae
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Card 2

Front

What is the virulent factor of vibrio cholera?

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cholera toxin (AB type)

Card 3

Front

What is the toxin of vibrio cholera encoded on?

Back

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Card 4

Front

What is the treatment for vibrio cholera?

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Preview of the front of card 4

Card 5

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What does bacteremia?

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