Metabolism 0.0 / 5 ? BiologyMetabolismUniversityNone Created by: kayCreated on: 16-05-19 20:53 Which is not a non-reversible step in glycolysis Citrate synthase 1 of 45 Adrenaline can directly influence which enzyme Phosphofructokianse II 2 of 45 Increasing the rate of phosphofructokinase 1 also indirectly increases the rate of Hexose kinase and pyruvate kinase 3 of 45 Pyruvate dehydrogenase makes which product Acetyl-CoA 4 of 45 Which is not a high energy molecule? AMP 5 of 45 Which molecules inhibit the TCA cycle? ATP, NADH, acetyl-CoA, citrate, succinyl CoA 6 of 45 During a high energy demand situation ATP is low, ADP is high 7 of 45 During a feast, you get fat because NADH inhibits a-ketoglurate DH and citrate accumulates 8 of 45 1 molecule of glucose makes 32 ATP 9 of 45 Of the 32 ATP molecules made 24 are by electron transport 10 of 45 What is the initial fuel in glycolysis? Glucose 11 of 45 What is the transport protein for glucose? GLUT 12 of 45 What controls the rate of glycolysis? Adrenaline 13 of 45 What enzyme is rate limited by it's own product in the first phosphorylation of glycolysis? Hexokinase 14 of 45 What is the type of inhibition caused when a product inhibits it's own enzyme? Feedback inhibition 15 of 45 What is the rate limiting enzyme in glycolysis controlled by three hormones? Phosphofructokinase I 16 of 45 What is the final control point enzyme named for the reverse reaction? Pyruvate kinase 17 of 45 What is a useless three carbon sugar molecule formed at the midpoint of glycolysis? Dihydroxyacetone Phosphate (DHAP) 18 of 45 What is the total yield of molecules that provide energy directly from glycolysis 4 ATP 19 of 45 What is the total energy invested in glycolysis 2 ATP 20 of 45 What adenine containing molecule is a mobile electron carrier without an electron? NAD 21 of 45 Where does glycolysis take palce? Cytoplasm 22 of 45 What is the product of anaerobic fermentation of pyruvate in humans? Lactate 23 of 45 What is the name of the cycle that breaks the product of anaerobic fermentation down? Cori cycle 24 of 45 What is released from tissues when ATP is completely dephosphorylated, causing vasodilation? Adenosine 25 of 45 What is an exergonic reaction? Negative change in free energy, spontaneous and release of energy 26 of 45 What is an endergonic reaction? Positive change in free energy, nonspontaenous and absorption of energy 27 of 45 What is an example of an exergonic reaction? Glucose -> Glucose 6-phosphate (using hexokinase) 28 of 45 What factor(s) affect rate of reversible enzymes? Concentration of substrate and product 29 of 45 If phosphofructokinase is stimulated, what happens to the reactant fructose 6-phosphate concentration? Decreases 30 of 45 If phosphofructokinase is stimulated, what happens to the rate of hexokinase? Increases 31 of 45 How many NADH is produced in the citric acid cycle? 6 32 of 45 How many FADH2 is produced in the TCA cycle? 2 33 of 45 How much final ATP is yieled from TCA cycle? 20 ATP 34 of 45 What is the role of hexokinase? Trapping glucose within the cell by phosphorylation 35 of 45 Which organ is an exception to hexokinase inhibition? Liver 36 of 45 At what stages are ATP produced in glycoylsis? 1,3-bisphosphoglycerate->3-phosphoglycerate AND Phosphenolpyruvate->Pyruvate 37 of 45 What does pyruvate kinase do? Adds a phosphate to ADP 38 of 45 What cofactor does hexokinase require to work? Magnesium 39 of 45 What stage(s) of glyoclysis uses ATP? Phosphorylation of glucose and Phosphorylation of fructose 6-phosphate 40 of 45 Why is glucose isomerised in glycolysis? To make it symmetrical 41 of 45 What is the role of aldolase in glycolysis? To divide fructose 1,6-phosphate into glyeraldehyde 3-phosphate 42 of 45 What is the reactant and product in the triose phosphate interconversion? Dihydroxyacetone phosphate to glyceraldehyde 3-phosphate 43 of 45 What type of phosphorylation synthesises ATP using inorganic phosphate from a substrate Substrate-level phosphorylation 44 of 45 What is the net gain of ATP from glycolysis? 2 ATP 45 of 45
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