MEM - 3 - Flashcards in University Psychology

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Created by: 10dhall
Created on: 04-05-17 13:34

What is synaptic plasticity?

increasing/ decreasing the strength of synapses over time as a response to increased/decreased activity

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What is LPD

Long-term potentiation - An increase in synapse strength following a high frequency stimulation of it

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What did Bliss and Lomo do?

Studied a rabbits hippocampus and found that when they stimulated the synapse, the strength of it increased - lasted for several hours

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Why are NMDA receptors important?

LTP needs NMDA receptors - APV is a NMDA antagonist (blocker) when induced, the LTP is reduced

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What did Le Doux do?

Fear conditioned rats by electrocuting them every time a tone was heard - increased synapses response = similar to LTP

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What did Ploski do?

Induced arc protein into the amygdala by stimulating the high frequency synapses

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What is LTD?

Long- term depression - opposite of LPD - low frequency stimulation can lead to wearing the strength of the synapse

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Use of LTD?

If there is an inhibitory neutron, it can be used to weaken the synapse between the input neutron and the inhibitory neutron, therefore the input neutron can more directly pass electrical activity to the output neuron

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What similarities does LTP share with memory?

Both LTM ans LTP require protein synthesis, Both require NMDA(study with NMDA receptor agonist showed LTP&LTM etc decreased), fear conditioning produces synaptic potential, high freq stim of amygdala produces arc(arc increases after learning)

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Other cards in this set

Card 2

Front

What is LPD

Back

Long-term potentiation - An increase in synapse strength following a high frequency stimulation of it

Card 3

Front

What did Bliss and Lomo do?

Back

Card 4

Front

Why are NMDA receptors important?

Back

Card 5

Front

What did Le Doux do?

Back

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MEM - 3