Maguire

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  • Created by: C
  • Created on: 10-03-15 09:10
Participants
Experimental: 16 male london taxi drivers, rght handed, passed the knowledge, mean age 44 Control: 16 male NTD
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Function of Hippocampus
Spacial memory and navagation - remembering locations and how to get to them
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Aim
To investiage if the brain of TD would have different morphology to NTD and further investigate the function of the hippocampus
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How was the data collected?
MRI scans
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2 techniques used to analyse data?
VBM (Voxel based morphometry) and Pixel Counting
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What is VBM?
Voxel based morphometry - comparing every brain to a template brain to see overall differences particularly grey matter density - the template brain was made from 50 healthy males MRI scans
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What was the template brain made from?
50 healthy males MRI scans
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What is pixel counting?
A researcher blind to the experiment counted the total pixels on an MRI image of a slice of the hippo campus (A - 6, B - 12, P - 6) a correction was made accoring to inter-cranial volume to account for people w/ larger skulls
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Results of VBM analysis
The only regions with increased grey matter in the TD was the R and L hippocampi - posterior, the controls had more grey matter in the anterior
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Results of pixel counting
The control group had larger antrior right hippocampus and had a larger R body than the left, Taxi drivers - larger posterior than controls
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Correlations
Time spent as a taxi driver postivley correlated with the volume of right posterior hippocampus, time spent as a TD negativly crrelated with volume of anterior hippocampi
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Card 2

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Function of Hippocampus

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Spacial memory and navagation - remembering locations and how to get to them

Card 3

Front

Aim

Back

Preview of the front of card 3

Card 4

Front

How was the data collected?

Back

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Card 5

Front

2 techniques used to analyse data?

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