Lymphoid- histology

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1. What are the formed elements of adult blood?
1. RBC, WBC, platelets
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2. Give some examples of granulocytes and agranulocytes
2. Granulocytes: neutrophils, eosinophils, basophils. Agranulocytes: lymphocytes and monocytes
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3. What is the major role of the adaptive system
3. Destruction and the ability to distinguish self from non self
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4. What is an autoimmune disease?
4. Lymphocytes react to self antigens, the immune system fails to distinguish between self and non self it attacks the body itself
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5. What tissue is attacked by the following autoimmune diseases: addison’s disease, myasthenia gravis, multiple sclerosis
5. Adrenal cortex, neuromuscular junction and CNS myelin
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6. What are lymphoid organs and how are they linked?
6. Organs of the immune system, linked by blood vascular and lymph vascular systems
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7. What are the primary and secondary lymphoid organs? Give examples
7. Primary lymphoid organs: sites of lymphocyte production and maturation- bone marrow and thymus. 2ry: sites to which lymphocytes migrate and where they aggregate in large numbers- spleen, lymph nodes, lymph nodules that are found in epithelia like
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8. What do NK. Cells do?
8. Kill virus infected cells and some tumour cells
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9. What happens to b and t cells after they are produced from stem cells in the bone marrow?
9. B cells remain in the bone marrow to continue their development and then go to 2ry lymphoid organs. Immature t cells migrate to the thymus to mature and be educated but most will be eliminated
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10. Where is the thymus located? What is it subdivided by?
10. In the mediastinum. By septa
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11. What is septa
11. Connective tissue and epithelioreticular cells which have epithelial properties
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12. What does the darkly staining cortes and lighter medulla contain?
12. Dark- large numbers if t cells (thymocytes) + epithelioreticular cells and macropahages. Light- mainly t cells larger and less densely packed and epithelioreticular cells
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13. What is hassall’s corpuscles?
13. Characteristic whorls of epithelial cells with keratin at their core
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14. What does the medulla of the lymph contain
14. Medullary sinuses and medullary cords that contain plasma cells and macrophages
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15. What are the functions of the spleen?
15. Produce immune response against blood borne antigens, removal of particulate matter and aged blood cells, production of blood cells during fetal life
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16. How do you know that red blood cells have reached the end iof their life?
red blood cells passing through the organ must leave the capillaries, pass through the parenchyma, and find their way back into venous sinuses through small spaces. Old RBC’s cannot deform and will lyse and be phagocytosed by macrophages associated
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continued
Old RBC’s cannot deform and will lyse and be phagocytosed by macrophages associated wth the wall of the sinuses.
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Card 2

Front

2. Give some examples of granulocytes and agranulocytes

Back

2. Granulocytes: neutrophils, eosinophils, basophils. Agranulocytes: lymphocytes and monocytes

Card 3

Front

3. What is the major role of the adaptive system

Back

Preview of the front of card 3

Card 4

Front

4. What is an autoimmune disease?

Back

Preview of the front of card 4

Card 5

Front

5. What tissue is attacked by the following autoimmune diseases: addison’s disease, myasthenia gravis, multiple sclerosis

Back

Preview of the front of card 5
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