Lustman - Fluoxetine for depression

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What was the aim of Lustman's research?
To assess the efficacy of the anti-depressant FLUOXETINE in treating depression by measuring glycemic control.
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What was the methodology of Lustman's research?
Randomised control double-blind study.
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Who were the participants in Lustman's study?
60 participants with diabetes, 26 had type 1 diabetes and 34 had type 2 diabetes.
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What was the procedure for Lustman's research?
Patients randomly assigned to either Fluoxetine group or placebo group. Study conducted over 8 weeks. Patients assessed for depression using psychometric tests and their adherence to medical regimes was measured by measuring their GHb.
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What were the findings collected from Lustman's study?
Patients using Fluoxetine reported lower levels of depression. They also had lower levels of GHb which indicted their improved adherence.
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What conclusions were drawn from Lustman's research?
Greater adherence was shown by patients who were less depressed. Measuring GHb in patients with diabetes indicates their level of adherence to prescribed medical regimes.
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What was the methodology of Lustman's research?

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Randomised control double-blind study.

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Who were the participants in Lustman's study?

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