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  • Created by: fifi212
  • Created on: 21-05-15 12:24
vertical pathway in neurotransduction
photoreceptors --> bipolar --> ganglion
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horizontal pathway in neurotransduction
mediated by glutamate. fro contrast, horizontal --> amacrine. Mainly inhibitory GABA
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optoneuropathy
phototransduction. No proper joining between ganglion cells and optic nerve i.e glucoma, MS
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retinal dystrophy
No photoreceptor transduction. AMD, retinitis pigmentosa (20s late teens)
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retinitis pigmentosa
rod degeneration (mutations in rhodopsin gene) night blindness, inherited, x-linked. Deafness also associated due to photoreceptors being similar structure and similar genes to cillia cells
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Treatment wet AMD
Anti VEGF factor --> causes vasoconstriction in the choroid and decreases vascular leak
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Treatment of dry AMD
complement factor D inhibitor (prevents drusen deposits through oxidation) i.e lampalizamub
7 of 8
Types of retinal implants
subretinal space and epiretinal space (ganglion cells)
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Card 2

Front

mediated by glutamate. fro contrast, horizontal --> amacrine. Mainly inhibitory GABA

Back

horizontal pathway in neurotransduction

Card 3

Front

phototransduction. No proper joining between ganglion cells and optic nerve i.e glucoma, MS

Back

Preview of the back of card 3

Card 4

Front

No photoreceptor transduction. AMD, retinitis pigmentosa (20s late teens)

Back

Preview of the back of card 4

Card 5

Front

rod degeneration (mutations in rhodopsin gene) night blindness, inherited, x-linked. Deafness also associated due to photoreceptors being similar structure and similar genes to cillia cells

Back

Preview of the back of card 5
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