L8 Pharm

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How do we measure affinity?
KD- conc of drug required to give 50% occupancy of receptors
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What is an agonist?
Binds receptor and produces biological response similar to endogenous ligand
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What is an antagonist?
binds receptor, no response, blocks a pathway and agonists.
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Give three examples of agonists
heroin, carbachol, phenylephrine
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What is a common type of antagonist?
Reversible competitive (so compete with agonist for target)
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Examples of antag are atropine, propanolol, heroin?
not heroin.
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What does propanolol do?
b-blocker, blocks NORADRENALINE.
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Card 2

Front

What is an agonist?

Back

Binds receptor and produces biological response similar to endogenous ligand

Card 3

Front

What is an antagonist?

Back

Preview of the front of card 3

Card 4

Front

Give three examples of agonists

Back

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Card 5

Front

What is a common type of antagonist?

Back

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