Kidneys and diuretics L1 and L2

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What is renal microcirculation and its role?
RBF through the glomerulus. Role to maintain constant hydrostatic pressure in glomerular capillaries
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What does net Glomerular Pressure determine?
the rate of filtrate flow through the glomerulus (Glomerular Filtration Rate- GFR)
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Tubule site which reabsorbs salts at the highest rate (60-70%)
Promximal convoluted tubule (PCT)
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Tell me about the carbonic anhydrase inhibitor, beyotch
acetazolamide: responsible for reabsorption of bicarbonate in the PCT, enzyme reversibly converts carbonic acid into carbon dioxide and water and vice versa
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Loop diuretics- where absorbed and where/how secreted? (pharmacokinetics)
absorbed in the gut, secreted into the tubular filtrate by OAT in the PCT
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renal effects of thiazides diretics?
lower Na+/Cl- reabsorption, Ca++ excretion. Higher K+ excretion
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Loop/thiazide diuretics non-renal related side effects?
erectile dysfunction with thiazides, reversible (LOL). Uncommon ones: loss of hearing (high doses), hypersensitivity reactions, blood disorders
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Other cards in this set

Card 2

Front

What does net Glomerular Pressure determine?

Back

the rate of filtrate flow through the glomerulus (Glomerular Filtration Rate- GFR)

Card 3

Front

Tubule site which reabsorbs salts at the highest rate (60-70%)

Back

Preview of the front of card 3

Card 4

Front

Tell me about the carbonic anhydrase inhibitor, beyotch

Back

Preview of the front of card 4

Card 5

Front

Loop diuretics- where absorbed and where/how secreted? (pharmacokinetics)

Back

Preview of the front of card 5
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