INF 2 - Intro to Immunology

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Lymphoid Cells:
B cells, T cells, NK cells
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Myeloid Cells:
Macrophage, Dendritic Cell, Neutrophil, Eosinophil, Basophil, Mast Cell
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Macrophage functions:
Phagocytosis, Antigen Presentation
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Dendritic Cell functions:
Antigen Presentation, T cell activation (in lymph nodes)
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Neutrophil functions:
Bacterial phagocytosis
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Eosinophil functions:
Kill Ab coated parasites
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Basophil functions:
Promotes allergic response, anti-parasitic
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What characterises lymphoid cells?
Large single nucleus
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Mast Cell functions:
Release histamine
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B Cell functions:
Produce Ab
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Neutralisation:
Ab binding with toxins to block receptor binding
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Opsonisation:
Ab binding with antigens to allow phagocytosis
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Complement activation:
Ab binding with antigens to activate complement system
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Types of T Cell:
CD8 / Cytotoxic , CD4 / Helper
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CD8 T Cell functions:
Kill infected cells
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CD4 T Cell functions:
Help B cell make Abs, help macrophages
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Which HLA do CD4 T Cells recognise?
Class II
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Which HLA do CD8 T Cells recognise?
Class I
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What cells are APCs?
Macrophages, Dendritic cells, B cells
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What do BCRs recognise?
Native antigen
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What do TCRs recognise?
Fragments of peptides presented by MHCs
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What are the primary lymphoid organs?
Bone marrow, Thymus
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Where do lymphoid progenitors originate?
Bone marrow
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Where do B cells develop?
Bone marrow
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Where do T cells develop?
Thymus
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What are the secondary lymphoid organs?
Lymph nodes, Spleen, Peyer's patches, lymphoid tissue
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Other cards in this set

Card 2

Front

Myeloid Cells:

Back

Macrophage, Dendritic Cell, Neutrophil, Eosinophil, Basophil, Mast Cell

Card 3

Front

Macrophage functions:

Back

Preview of the front of card 3

Card 4

Front

Dendritic Cell functions:

Back

Preview of the front of card 4

Card 5

Front

Neutrophil functions:

Back

Preview of the front of card 5
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