INF 16 - Emerging Bacterial Interactions 1

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What does emerging infection mean?
Infections that have newly appeared in a population or have existed previously but are rapidly increasing in incidence or geographic range
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What does re-emerging infection mean?
Those that have existed in the past but are now rapidly increasing either in incidence or geographical or human host range
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What factors are responsible for decreasing incidence of infectious disease?
Decrease in host susceptibility, Decrease in disease transmission
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What decreases host susceptibility?
Better housing, better nutrition, Antibiotics
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What decreases disease transmission?
Safer food and water, Immunisations, improved hygiene and sanitation
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What factors are responsible for increasing incidence of infectious disease?
Increase in host susceptibility, Increase in disease transmission, New diseases
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What increases host susceptibility?
Changes in industry, changes in behaviour, environmental change
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What increases disease transmission?
Travel, microbial change
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What causes new diseases?
Breakdown of public health
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How does Mtb enhance HIV susceptibility?
Activates NF-kb, drives HIV replication
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What does rifampicin disrupt?
Inhibits RNA Polymerase - Transcription
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What do Isoniazid, pyrazinamide, ethambutol affect?
Outer layers of bacteria
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What mutation confers isoniazid resistance?
KatG
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What mutation confers rifampicin resistance?
RNAP
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Other cards in this set

Card 2

Front

What does re-emerging infection mean?

Back

Those that have existed in the past but are now rapidly increasing either in incidence or geographical or human host range

Card 3

Front

What factors are responsible for decreasing incidence of infectious disease?

Back

Preview of the front of card 3

Card 4

Front

What decreases host susceptibility?

Back

Preview of the front of card 4

Card 5

Front

What decreases disease transmission?

Back

Preview of the front of card 5
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