1. In order to arm the Th2 cell during activation, a co-stimulatory signal is required. Between which molecules does this occur? (First molecule(s) = on dendritic cell, Second molecule(s) = on Th2 cell)
- CD28 & CD40/CD46
- CD28 & CD80/CD86
- CD80/CD86 & CD28
- CD40/CD46 & CD28
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Other questions in this quiz
2. When an allergen comes into contact with an allergic airway, what happens to the FEV1?
- Sharp decrease
- Sharp increase
- Gradual decrease
- Gradual increase
3. Activated Th2 cells secrete cytokines. What are the main roles of cytokines?
- To regulate inflammation, proliferation and differentiation of inflammatory cells
- To bind to antigens and destroy them
- To bind to bacterial/viral toxins and destory them
- To induce apoptosis in epithelial cells
4. Which of the following are changes seen in the asthmatic lung?
- Thickening of the lamina reticularis with collagen
- Thinning of the lamina reticularis
- Thickening of the lamina propria with elastin
- Thickening of the basal lamina with smooth muscle
5. Identify the correct actions of histamine from the list below.
- Opens capillary bed & therefore increases blood flow to the affected area
- Regulates IL-4 & IL-13 in order to then regulate the inflammatory response
- Secretes proteolytic enzymes and TNF-alpha
- Secretes IL-4 & IL-13 in order to regulate the inflammatory response