Immunology 0.0 / 5 ? MedicineImmunologyUniversityNone Created by: MazzaWCreated on: 12-11-19 10:33 State that macrophages are in when they act as sentinels Resting 1 of 15 IFNg is released by T cells and: Natural killer cells 2 of 15 Cascade that is activated when macrophages release TNFa Complement 3 of 15 Which cells are activated by IFNg or TLR stimulation? Dendritic cells 4 of 15 What chemical is secreted to promote monocyte recruitment to the site of infection? Chemokines 5 of 15 B-cells need T-cell help to proliferate, form _____ centres and proliferate Germinal 6 of 15 What do T-cells constantly need at the site of infection to prevent them apoptosing? Restimulation 7 of 15 What cells are the best at antigen presentation in the early stages of reinfection? B cells 8 of 15 Failure/cessation of survival signals is the ____ cell death pathway Intrinsic 9 of 15 Activation of death receptors is the ____ cell death pathway Extrinsic 10 of 15 What system ensures T-cells have a hard-wired sense of self and non-self? Thymic selection 11 of 15 Deficiency of what leads to organ-specific autoimmunity and chronic mucocutaneous candidiasis? AIRE 12 of 15 Mutation in FOXP3 causes what syndrome? IPEX 13 of 15 Unresponsiveness to an antigen is known as what? Tolerance 14 of 15 _____ T cells enforce tolerance and suppress effector functions of other immune cells Regulatory 15 of 15
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