IB Standard Biology: cells (phospholipid bilayer)

?
What is a Phospholipid made up of?
Hydrophilic (polar) head and 2 Hydrophobic (non-polar) tails
1 of 19
Why is the phospholipid bilayer able to maintain its structure?
heads weakly associated to extracellular fluid and tails weakly associated to each other = membrane can be fluid/move
2 of 19
What is an integral protein?
proteins that span the membrane
3 of 19
What is an peripheral protein?
proteins found on one side of the membrane
4 of 19
What is the anagram enzymes found in the Phospholipid bilayer?
C(e)C(e)G(rows)PEA(s in)N(orth)H(ampton)
5 of 19
What is the C?
Carrier protein - transport macromolecules (too large to fit through phospholipid bilayer)
6 of 19
What is the C?
Channel protein - transport charged (polar/ionic) molecules
7 of 19
What is the G?
Glycoprotein/receptor protein - for hormone binding and cell recognition by immune system
8 of 19
What is the P?
Protein pump - for Active transport
9 of 19
What is the E?
Enzymes - catalyse reactions
10 of 19
What is the A?
Adhesion protein - bind cells together
11 of 19
What is the N?
Neurotransmitter receptor protein - allows communication between cells
12 of 19
What is the H?
Hormone receptor protein - bind to specific hormones, causing conformational shape change which starts chemical process in cell
13 of 19
What is the function of Cholesterol in the Phospholipid bilayer?
immobilises phospholipids= improves rigidity, reduces fluidity and permeability of membrane
14 of 19
What was the Davson-Danielli model (1935) of the phospholipid bilayer?
'sandwich' = proteins coat either side (but don't permeate) the phospholipid core
15 of 19
How was this model developed?
using magnified electron micrographs, images showed 2 dark parallel lines (interpreted as proteins) with a lighter middle (interpreted as phospholipids)
16 of 19
Which 3 things disproved it?
1) freeze-fracture=membrane sprayed with heavy metal and split, showing integral proteins 2)Globular=cells found to be globular (with bumps on surface), not fibrous 3)Antibody tagging=antibodies dispersed in membrane (membrane proteins free to move)
17 of 19
What is the current model of the phospholipid bilayer called?
Singer- Nicholson model (1972) / fluid mosaic model
18 of 19
How is it different from the Davson Danielli model?
includes integral proteins, disproved the 'flanking' proteins (protein coat) idea
19 of 19

Other cards in this set

Card 2

Front

Why is the phospholipid bilayer able to maintain its structure?

Back

heads weakly associated to extracellular fluid and tails weakly associated to each other = membrane can be fluid/move

Card 3

Front

What is an integral protein?

Back

Preview of the front of card 3

Card 4

Front

What is an peripheral protein?

Back

Preview of the front of card 4

Card 5

Front

What is the anagram enzymes found in the Phospholipid bilayer?

Back

Preview of the front of card 5
View more cards

Comments

No comments have yet been made

Similar Biology resources:

See all Biology resources »See all Cellular processes and structure resources »