Histology- Epithelium and Skin

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  • Created by: Ruth
  • Created on: 04-02-13 12:16
What is epithelium?
A tissue consisting of closely packed cells with ECM, covering all body surfaces.
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What are the characteristics of epithelium?
Cell adhesion mechanisms nchoring cytoskeleton of adjacent cells and to the basal lamina.
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Are there blood vessels in epithelium?
NO only epithelium.
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How is epithelium classified?
Number of cells, shape of cells, presentation of cell surface.
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How is epithelium arranged?
Epithelium, basal lamina, connective tissue.
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What are the eight types of epithelium?
Simple: squamous, cuboidal, collumnar, Stratified: squamous, cuboidal, collumnar .Pseudo Stratified, transitional epithelium.
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Simple Squamous
Lung and Blood vessels
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Simple Cuboidal
Small ducts eg in Kidney
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Simple collumnar(babies in blankets)
Present in GI tract and stomach
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Stratified Squamous
Skin, oesophagus, vagina and anus
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Stratified cuboidal
Large Ducts such as mammory glands. Protective function.
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Stratified collumnar
Conjunctiva
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Pseudo Stratified
Respiratory tract
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Transitional
Urinary tract, withstands toxicity.
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Name the function of each of these types of epithelium.
How does this relate to the type of epithelium and the position in the body?
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What are the types of cell adhesions within epithelium?
Occluding junctions, anchoring junctions and gap junctions.
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What are occluding junctions?
Occluding junctions prevent the transfer of molecules between adjacent cells therefore contributing to the barrier functions of epithelium. The intra membrane proteins intertwine and “stitch” cells together.
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What are anchoring junctions? How many types are there? Name them
Anchor cells. Four types: Adherent, Desmosomes, Hemidesmosomes and focal contacts.
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What are adherent junctions?
Adherent junctions connect the cytoskeletons of adjacent cells using intracellular link proteins and trans membrane link proteins. This allows coordinated movement and is important in embryogenesis.
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What are Focal contacts?
Focal contacts use integrins(a type of trans membrane protein) to link the cytoskeleton to the ECM.
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What are desmosomes?
Desmosomes provide mechanical strength and have trans membrane proteins protruding from a plaque within the cell.
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What are Hemidesmosomes?
Hemidesmosomes are like desmosomes but link cells to the ECM.
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Which are important in embreyological development?
Adherent
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Which use the proteins integrin?
Focal contacts
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Which connect to the ECM?
Hemidesmosomes, focal contacts
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Card 2

Front

What are the characteristics of epithelium?

Back

Cell adhesion mechanisms nchoring cytoskeleton of adjacent cells and to the basal lamina.

Card 3

Front

Are there blood vessels in epithelium?

Back

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Card 4

Front

How is epithelium classified?

Back

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Card 5

Front

How is epithelium arranged?

Back

Preview of the front of card 5
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