what is incorrect about the biomarker Creatine Kinase?
extracellular enzyme
3 of 31
what is incorrect about the biomarker Troponin?
Troponin I binds to actin thin filaments and induces contraction
4 of 31
what symptom is not needed to diagnose MI (increase in cardiac marker and one of these)?
imaging evidence of gain of myocardium
5 of 31
if there is only an increase in biomarkers and no other findings indicitive of MI, what would you be diagnosed with?
acute coronary syndrome
6 of 31
what cannot cause congestive heart failure?
inappropriate platelet activation
7 of 31
what is false about the biomarker for congestive heart failure?
released in tissue damage
8 of 31
which prognosis if ischaemic stroke is false?
58% complete neurological recovery
9 of 31
what fact about arterial thrombosis is false?
atherosclerosis only occurs in veins
10 of 31
which fact about venous thrombosis is false?
venous circulation returns to the heart via the pulmonary vein into the capillary beds of the lungs, where emboli could get stuck (pulmonary embolism)
11 of 31
what is not a sign of deep vein thrombosis
bilateral heat in legs (calor), swelling (tumor), redness (rubor), pain in legs (dolor)
12 of 31
which statement is false about DVT?
10% risk of fatal pulmonary embolism
13 of 31
what does anti-thrombin III deficiency not affect?
prothrombin
14 of 31
what is false about anti-thrombin III deficiency?
90% develop a clot in lifetime
15 of 31
what is false about protein C deficiency?
serine protease that inhibits fibrinolysis
16 of 31
what is false about protein S deficiency?
can cause purpura fulminans in adult life (ormation of blood clots within small blood vessels throughout the body. These blood clots disrupt normal blood flow and can lead to necrosis)
17 of 31
what is false about Factor V Leiden?
autosomal recessive on chromosome 1
18 of 31
what is false about prothrombin G20210A allele?
decreased prothrombin levels
19 of 31
what is incorrect about Dysfibrinogenaemia
congenital anatomic variation that predisposes to a DVT in leg due to compression of left common iliac vein
20 of 31
what is false about thrombocytosis/thrombocytheamia?
secondary = reduction in platelet production due to infection
21 of 31
what does not lead to acquired thrombophilia?
genetics
22 of 31
what is not characteristic of Polycythaemia Rubra Vera?
thinned blood
23 of 31
which statement about paroxysmal nocturnal haemoglobinuria
inherited disorder
24 of 31
what is false about thrombocytopenia
identified by high platelet count
25 of 31
what is false about idiopathic thrombocytopenic purpura (sudden onset)?
spontaneous remission is 90% in acute and chronic disorders
26 of 31
what is false about Non-immune thrombotic thrombocytopenic purpura?
coagulation is normal in TTP, diagnosed through thrombocytopenia, schistocytosis (fragmented RBCs), elevated serum lactate dehydrogenase value (due to lysed cells)
27 of 31
what is correct about von Willebrand Disease?
type 1 = quantitive partial deficiency, type 2 = functional abnormality, type 3 = complete deficiency
28 of 31
what is false about vWD diagnosis?
high vWF and FVIII
29 of 31
what does not cause aquired impaired clotting?
haemophillia
30 of 31
which statement is false about Haemophilia A?
deficiency in FIX
31 of 31
Other cards in this set
Card 2
Front
what is incorrect about the biomarker LDH?
Back
released upon Ca ion activation
Card 3
Front
what is incorrect about the biomarker Creatine Kinase?
Back
Card 4
Front
what is incorrect about the biomarker Troponin?
Back
Card 5
Front
what symptom is not needed to diagnose MI (increase in cardiac marker and one of these)?
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