Give an example of intragranular substances which are released during platelet activation
Thromboxin A2, ADP
4 of 12
Activated platelets signal to other platelets to activate or attract other platelets to the site of activation through which signalling mechanism?
Paracrine
5 of 12
What is alpha II b beta 3?
Platelet cell surface receptor
6 of 12
Which conformation is alpha II b beta III in when the platelet is at rest?
Low affinity
7 of 12
Which ligand binds to alpha II b beta III?
Fibrinogen
8 of 12
What is fibrinolysis?
The degradation of a fibrin clot
9 of 12
Which active substance degrades the fibrin during fibrinolysis?
Plasmin
10 of 12
Which enzyme converts plasminogen into plasmin?
tPA, uPA
11 of 12
What is the complex formed when activated platelets cause the flipping of phosphatidyl serine to the outer membrane surface so that clotting factors can bind?
Prothrombinase complex
12 of 12
Other cards in this set
Card 2
Front
Which enzyme cleaves fibrinogen into fibrin?
Back
Thrombin
Card 3
Front
Which enzyme cleaves prothrombin into thrombin?
Back
Card 4
Front
Give an example of intragranular substances which are released during platelet activation
Back
Card 5
Front
Activated platelets signal to other platelets to activate or attract other platelets to the site of activation through which signalling mechanism?
Comments
No comments have yet been made