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Card 6

Front

Describe general activation of RTKs

Back

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Card 7

Front

What mechanisms of RTK over-activation lead to oncogenic transforation

Back

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Card 8

Front

The Philadelphia chromosome forms as a result of

Back

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Card 9

Front

How does Gleevec work

Back

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Card 10

Front

Name an EGFR orphan receptor

Back

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Card 11

Front

Which EGFR family members form heterodimers?

Back

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Card 12

Front

How does HER2 prevent endocytosis

Back

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Card 13

Front

How does binding of EGF cause EGFR dimerisation?

Back

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Card 14

Front

What four signalling cascades are involved in EGFR signalling?

Back

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Card 15

Front

Name an oncoproteins in the Ras/MAPK pathways and their effect

Back

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