Glycolysis

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  • Created by: Beth
  • Created on: 21-01-14 11:47
Definition: Glycolysis
The metabolic pathway where each glucose molecule is broken down to 2 pyruvate molecules.
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Glucose (6C)
One ATP molecule is hydrolysed and the phosphate group released is attactched to the glucose molecule at carbon 6 to form glucose 6-phosphate
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Glucose 6-Phosphate
Glucose 6-phosphaet is changed to fructose 6-phosphate
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Fructose 6-Phosphate
Another ATP is hydrolysed and the phosphate group released is attatched to fructose 6-phosphate at carbon 1. This activates hexose sugar is now called fructose 1,6-bisphosphate
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Hexose 1, 6-Bisphosphate
The energy from the hydrolysed ATP molecules ativates the hexose sugar and prevents it from being transported out of the cell.
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How many ATP are used during Phosphorylation?
2 molecules of ATP for each glucose molecule
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2 x Triose Phosphate (3C)
Each Molecule of hexose bisphosphate is split into 2 molecules of triose bisphosphate
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(Oxidation of triose phosphate) (1)
2H are removed from each triose phosphaet molecule (using dehydrogenase enzymes)
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(Oxidation of triose phosphate) (2)
This is aided by the coenzyme NAD, which is a hydrogen acceptor. NAD combines witht the hrdrogen atoms to become reduced NAD.
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2 x Intermediate compound (3C)
2 molecules of NAD are reduced per molecule of glucose. 2 ATP molecules are formed - substrate-level phosphorylation.
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2 x Pyruvate (3C)
4 enzyme-catalysed reactions convert each triose phosphate molecule to a molecule of pyruvate (3C).
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(Conversion of triose phosphate to pyruvate)
2 molecules of ADP are phosphorylated (inorganic P group added) to 2 molecules of ATP (substrate-level phosphorylation)
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Products of Glycolysis
2 ATP, 2 NADH and 2 Pyruvate
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Other cards in this set

Card 2

Front

One ATP molecule is hydrolysed and the phosphate group released is attactched to the glucose molecule at carbon 6 to form glucose 6-phosphate

Back

Glucose (6C)

Card 3

Front

Glucose 6-phosphaet is changed to fructose 6-phosphate

Back

Preview of the back of card 3

Card 4

Front

Another ATP is hydrolysed and the phosphate group released is attatched to fructose 6-phosphate at carbon 1. This activates hexose sugar is now called fructose 1,6-bisphosphate

Back

Preview of the back of card 4

Card 5

Front

The energy from the hydrolysed ATP molecules ativates the hexose sugar and prevents it from being transported out of the cell.

Back

Preview of the back of card 5
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