Genomics and pharmacology

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How do you clone a receptor gene
extract mRNA --> convert to cDNA--> PCR--> screen with ligand-->sequence
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How is are muscarinic and nicotinic receptor different?
Muscarinic is G-protein coupled. Nicotinic receptors are ligand-gated ion channels need up to four genes. two binding points
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What are orphan receptors?
receptors without ligand/not known. Use a sequence of a receptor to find other commone receptors from a database.
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Card 2

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How is are muscarinic and nicotinic receptor different?

Back

Muscarinic is G-protein coupled. Nicotinic receptors are ligand-gated ion channels need up to four genes. two binding points

Card 3

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What are orphan receptors?

Back

Preview of the front of card 3

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Preview of the front of card 4

Card 5

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