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6. How many populations does the HapMap Project phase 2 include
7. What does this describe? 20,000-25,000 genes, used to identify the 3 billion base pairs of our genome, to store information for all public
- Human Genome Project
- HapMap Project
8. what can selection bias cause
- population stratification
- information bias
9. 0 copy is...
- commom homozygote
- rare homozygote
- heterozygote
10. 1 Copy is ....
- Rare Homozygote
- commom homozygote
- heterzygote
11. What is the correct order for the historical overview of gene discovery?
- Descriptive Epidemiology, segregation analyses, familial aggregation, heritability studies
- Descriptive Epidemiology, familial aggregation, segregation analyses
- Descriptive Epidemiology, familial aggregation, heritability studies, segregation analyses
- Descriptive Epidemiology, heritability studies, familial aggregation, segregation analyses
12. What did segregation analyses do
- estimated the genetic model of a disease by looking at the multigenerational family data
- confirmed that environment was responsible for development of chronic disease
- confirmed that genes cannot be segregated with the disease when it is translated
13. What is Descriptive Epidemiology?
- Describing the disease and noticing that the DNA Genotype contributes to the DNA Phenotype as well as prevalence from different populations
- Just a description of the disease and what symptoms it has
- A description of the disease and its prevalence from one population to another
14. It can only look at common variants not rare ones is a disadvantage of what project?
- HapMap Project
- Human Genome Project
15. The main advantage of the HatMap Project is that it takes into consideration LD, but what is complete LD?
- When the genetic variations are inherited together
- When the genetic variations are inherited not together
16. If you were to do a case control status analysis e.g. disease and cut point what stats test would you do?
- Logistic regression analysis (P value + odds value)
- Linear Regression Analysis (P Value)
17. 2 copy is .....
- Heterozygote
- common homozygote
- rare homozygote
18. Categorical and Quantitative are examples of what?
- Outcomes
- Exposure
- Design
- Co-variables
19. Co-founding is a disadvantage of candidate gene studies, but what is it?
- when there is a third variable that affects exposure and disease outcomes and gives false findings e.g. ethnicity
- when there is a second variable that affects the disease/ trait for example exposure
- when there are many variables but these are all considered in the study
20. Is candidate gene studies hypotheses or not driven?
- Hypothesis- driven
- Non Hypothesis Driven