Genetically engineered drugs 0.0 / 5 ? PharmacyGenetic engineeringUniversityNone Created by: RscottqubCreated on: 07-03-19 21:06 Why doe we need GE drugs? lots of diseases are treated by protein based drugs, these proteins are far too complex to be made via organic synthesis 1 of 6 Why cant we use proteins from human plasma HIV, Hep C , CJD, also would be far too expensive - 100L of plasma would be required to obtain 1mg of EPO 2 of 6 origin of replication site on DNA where the host cells replication enzymes recognize it 3 of 6 Before DNA recombinant tech what was used to produce insulin Porcine insulin, 1 AA substituted --> human insulin 4 of 6 Factor VII a A def can cause excess bleeding after surgery/trauma - basically prevents the cascade of enzyme linked events for the blood to clot 5 of 6 How is Factor 7a produced from BHK cells - baby hamster kidney cells 6 of 6
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