Genetic Explanation of OCD

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Why do we develop OCD according to the genetic explanation?
It is the result of a gene which you have inherited
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What did Carey 1981 find?
With identical twins there was 87% chance that if one twin developed OCD so would the other and if the twin
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What did Pauls et al do?
Interviewed first degree family members for signs of OCD
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What did Pauls et al find?
Rates of OCD in family was 10% compared to healthy controls (2%)
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What is the average chance of developing OCD?
1-3% chance
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Which gene did Woods 2008 state stopped mice developing trichotillomania?
Hoxb8
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What happen when a litter of mice were bred without this gene?
Every mouse in the litter licked and nibbled until they were bald
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What does this suggest?
There may be specific genes for types of OCD
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Which gene did Feng et al say caused OCD in humans?
The sapap 3 gene
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There is consistent evidence that...
Genes play a role
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Relatives also share...
A similar environment so it may not be a clean measure
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Sharing an environment with someone...
With OCD may cause stress which brings on OCD
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Why must there be other factors which play a role?
Because the concordance rates are not 100%
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Card 2

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What did Carey 1981 find?

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With identical twins there was 87% chance that if one twin developed OCD so would the other and if the twin

Card 3

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What did Pauls et al do?

Back

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Card 4

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What did Pauls et al find?

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Card 5

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What is the average chance of developing OCD?

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