fMRI

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What does BOLD fMRI stand for?
Blood-Oxygen-Level Dependent
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Why is blood "magnetic"?
Based on whether or not hemoglobin in red blood cells is carrying oxygen
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Oxyhemoglobin is ..
Diamagnetic (not magnetic)
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What does oxyhemoglobin do to signal?
Increases signal a bit and makes image brighter
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Deoxyhemoglobin is...
Paramagnetic (magnetic)
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What does deoxyhemoglobin do to signal?
Decreases it a lot and makes image darker
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What is the total of deoxy and oxyhemoglobin called?
Total hemoglobin or cerebral blood volume
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Deoxyhemoglobin appears when the brain extracts .... for metabolism
Oxygen
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What would we expect to happen?
Deoxyhemoglobin would increase as oxygen is used up
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Why does this not happen?
Because flow increases so much
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Therefore ..... of hemoglobin leads to increase in fMRI signal
Washing away
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What increases in specific region following presentation of stimulus?
Cerebral blood flow
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This is stronger than what?
Greater than any oxygen consumption
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However what is "a dip" that occurs at the start of the process?
Increase in deoxyhemoglobin
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What does this cause?
Temporary dip in fMRI signal
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Other cards in this set

Card 2

Front

Why is blood "magnetic"?

Back

Based on whether or not hemoglobin in red blood cells is carrying oxygen

Card 3

Front

Oxyhemoglobin is ..

Back

Preview of the front of card 3

Card 4

Front

What does oxyhemoglobin do to signal?

Back

Preview of the front of card 4

Card 5

Front

Deoxyhemoglobin is...

Back

Preview of the front of card 5
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