FCB

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  • Created by: rkerri200
  • Created on: 13-08-19 12:08
Which lipid is negatively charged AND predominantly located in the cytosolic leaflet of the plasma membrane?
Phosphatidylserine
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Which is NOT a membrane constituent?
Proteoglycan
2 of 36
Which of the following comments about LIPID-ANCHORED membrane proteins is TRUE?
The hydrocarbon chain of the lipid anchor is embedded in the lipid bilayer
3 of 36
Which of the following terms correctly describes the type of transport mediated by antiporters?
Secondary active transport
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What describes the speed of transport (fastest first) of ATPases, carriers and ion channels
Ion channels, carriers, ATPases
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What plays the major role in maintaining plasma membrane potential?
K+ leak channel
6 of 36
What undergoes targeted (specific) transcytosis in intestinal cells?
Maternal antibodies
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Which cells can mediate phagocytosis?
Macrophages
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What is the pH of a lysosome?
pH 5.0
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What CAN be employed to restrict the mobility of plasma membrane proteins?
Tethering to the cytoskeleton
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In which vesicles would you expect to see a bacteria ultimately destined for lysosomal degradation?
Phagosome
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What cannot diffuse directly (passively) across the plasma membrane?
Na+
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What types of transport is mediated by ion channels?
Facilitated diffusion
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What term describes ‘cell drinking’
Pinocytosis
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Which ATPase operates in ‘reverse’ to generate ATP?
F-type ATPase
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Receptor mediated endocytosis involves hydrolysis of?
GTP
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What is the fate of the EGF receptor following endocytosis?
Degradation in lysosomes
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Which phosphoinositide is involved in actin polymerisation and pseudopod formation?
PIP2
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How are senescent red blood cells removed from the body?
Phagocytosis
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Which phospholipids can stimulate phagocytosis?
Phosphatidylserine
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The mouse represents an excellent model for human disease because:
It has a short breeding cycle
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Epithelial tissue comprises cells that are:
Line the lumen of tissues exposed to the external environment
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To isolate and culture mammalian cells you need to:
Maintain the isolated cells isotonic media that is supplemented with serum to provide growth factors
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A western blot relies on:
Separation of proteins by SDS PAGE followed directly by probing with specific antibodies targeted to the protein of interest.
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The principles of immunofluorescence dictate that:
The fluorescent probe absorbs light at one wavelength and emits it at a longer wavelength
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what components of the cytoskeleton have catalytic activity?
Microtubules and microfilaments have catalytic activity
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What are lamins?
Lamins are intermediate filaments found in the nucleus
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Intermediate filaments :
Have no enzymatic activity
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Microfilaments are composed of :
Two protofilaments composed of G actin with ATP hydrolysis
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The nucleation core of microtubules is:
A preformed gamma tubulin ring that is located near the centrosomes
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Contractile bundles of microfilaments are associated with:
Anti-parallel alignments of actin filament associated with actinin dimers
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Myosin II is :
A plus end motor protein that interacts with anti-parallel alignments of actin microfilaments
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Kinesins are proteins that
Have two globular heads with ATP activity, one of which is always associated with the microtubule
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Stathmin is a protein that:
Traps alpha/beta tubulin dimers in the cytoplasm and restricts microtubule growth
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Treadmilling ensures that:
The rate of addition of actin monomers at the plus end equals the rate of loss at the minus end
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Within a neuron microfilaments are:
Are highly clustered tighter into parallel arrays held together by MAP2 and Tau proteins
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Other cards in this set

Card 2

Front

Which is NOT a membrane constituent?

Back

Proteoglycan

Card 3

Front

Which of the following comments about LIPID-ANCHORED membrane proteins is TRUE?

Back

Preview of the front of card 3

Card 4

Front

Which of the following terms correctly describes the type of transport mediated by antiporters?

Back

Preview of the front of card 4

Card 5

Front

What describes the speed of transport (fastest first) of ATPases, carriers and ion channels

Back

Preview of the front of card 5
View more cards

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