F222 - 2.1.1.3 - The cell cycle and apoptosis

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What are the 3 stages of interphase?
growth, synthesis and growth
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What are the four stages of mitosis?
Prophase, Metaphase, Anaphase and telophase
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what controls the timing and duration of the cell cycle?
protein complexes called
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Name the two protein complex involved in the cell cycle?
cyclins and cyclin-dependant kinases
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Name the 3 important checkpoints in the cell cycle?
Growth 1, Growth 2 and metaphase
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cyclins and CDK's are affected by signals where in the cell?
inside and outside the cell
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name two outside factors which could affect cyclins and CDK's?
hormones and drugs
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What do outside factors do to cyclins and CDK's?
bind to potein receptors on the surface of the plasma membrame
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What is the process called when cells kill themselves?
apoptosis
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How is apoptosis controlled?
by signals inside or outside the cell
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What happens after the cell shrinks?
the DNA and protein in the nucleus breaks down
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what happens after the mitochondria breaks down?
the cell breaks up into smaller fragments
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are the smaller fragments of the cell membrane bound?
yes
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The phospholipid which is present on the inside of the membrane and moves to the outside of the membrane?
phosphatidylserine
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What type of cells have protein receptors which recognize phosphatidylserine?
macrophages
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what do the macrophages do one they have binded to the receptors?
engulf the membrane bound fragments
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what are the two main reasons for cells committing apoptosis?
cells that are infected with viruses or have DNA damage
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3 examples of apoptosis in normal development?
the skin inbetween the fingers and toes, shedding of the uterus during menstruation and the death of surplus cells around synapses
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Other cards in this set

Card 2

Front

What are the four stages of mitosis?

Back

Prophase, Metaphase, Anaphase and telophase

Card 3

Front

what controls the timing and duration of the cell cycle?

Back

Preview of the front of card 3

Card 4

Front

Name the two protein complex involved in the cell cycle?

Back

Preview of the front of card 4

Card 5

Front

Name the 3 important checkpoints in the cell cycle?

Back

Preview of the front of card 5
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