Epigenetics, miRNAs and chromatin modification

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  • Created by: Fitzalice
  • Created on: 04-05-18 09:13

1. Relationship between Lin-28 and Let-7

  • Lin 28 negatively regualtes Let-7 activity in L1
  • Lin 28 negatively regualtes Let-7 activity in L2
  • Lin 28 negatively regualtes Let-7 activity in L3
  • Lin 28 negatively regualtes Let-7 activity in L4
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Other questions in this quiz

2. What happens in the 2nd cell division of C.elegans in the hypodermal cell lineage

  • 2 anterior cells differentiate into hypodermal cells and the 2 posterior cells remain as stem cells
  • 2 anterior cells differentiate into hypodermal cells and the 1 posterior cells remain as stem cells
  • 1 anterior cells differentiate into hypodermal cells and the 2 posterior cells remain as stem cells

3. Down regulation of Lin41 in L4 is due to

  • Upregualtion of Let-7
  • Down-regualtion of Let-7

4. ZEB1 and ZEB2 are

  • transcriptional repressors of E-cadherin, and activators of EMT genes
  • transcriptional activators of E-cadherin, and activators of EMT genes
  • transcriptional repressors of E-cadherin, and repressors of EMT genes

5. How is Par downregulated

  • By a miRNA induced by TGF beta signalling
  • By a miRNA activated by TGF beta signalling
  • By a miRNA repressed by TGF beta signalling

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