Eoin - Researchers for Schizophrenia

... of total disease burden in 2010 was attributed to mental health problems.
1 of 20
Psychosis is a broad term for...
clusters of symptoms (e.g. hallucinations/delusions)
2 of 20
Schizophrenia is a form of
3 of 20
W.H.O. described schizophrenia as what?
A severe mental disorder
4 of 20
A.P.A. described schizophrenia as what?
A chronic brain disorder
5 of 20
Schizophenia is characterised by...
hallucinations, delusions, disorganised speech, and other symptoms that cause social/occupational dysfunction
6 of 20
Symptoms must present for how long for DSM criteria?
6 months, including 1 month of active symptoms
7 of 20
Schizophreniform disorder is what?
Schizophrenia symptoms for <6 months
8 of 20
Schizoaffective disorder is what?
Schizophrenia but also presenting with symptoms of either depression or mania.
9 of 20
Guloksuz et al.
Schizophrenia ignores evidence that psychosis expression is continuously distributed across the general population, would be better expressed dimensionally than categorically.
10 of 20
Simeone et al. (2015)
First systematic review of schizophrenia prevalence in general populations published since 2005. Affects men/women about equally. Median 12 month prevalence rate 0.33% , lifetime prevalence rate 0.48%
11 of 20
Simeone et al (2015) - Prevalence amongst general populations varied by:
study design, study quality, geographic region, and time of assessment
12 of 20
Hilker et al. studied how many twin pairs?
13 of 20
Hilker et al.
33% concordance rate with monozygotic twins for schizophrenia, 7% for dizygotic twins
14 of 20
Strengths of Hilker et al.'s study?
Censoring was adjusted for this model for heritability estimates, and that improved method was applied to the nationwide twin samples to find participants.
15 of 20
What is proposed to cause positive schizophrenia symptoms?
Excessive dopamine, as supported by research conducted on Parkinson's patients who were given L-Dopa, a dopamine precursor, and when the dose was too high they displayed positive symptoms.
16 of 20
Anti-psychotics work by primarily blocking what?
Dopamine (D2) receptors
17 of 20
Why don't antipsychotics treat all symptoms of schizophrenia?
They only treat the positive symptoms, ineffective at treating negative symptoms/cognitive deficits of schizophrenia
18 of 20
Rothman et al. (2003)
Excitatory neural activity is primarily glutamatergic. 60-80% of brain's metabolic activity comes from gluamatergic activity.
19 of 20
The multiple areas of the brain thought to be involved in schizophrenia are connected by a circuit of brain cells that rely on...
glutamate to communicate. It is therefore believed that insufficient/excessive glutamate activity may cause schizo. symptoms due to the interactions with other neurotransmitters such as dopamine or GABA
20 of 20

Other cards in this set

Card 2


Psychosis is a broad term for...


clusters of symptoms (e.g. hallucinations/delusions)

Card 3


Schizophrenia is a form of


Preview of the front of card 3

Card 4


W.H.O. described schizophrenia as what?


Preview of the front of card 4

Card 5


A.P.A. described schizophrenia as what?


Preview of the front of card 5
View more cards


No comments have yet been made

Similar Psychology resources:

See all Psychology resources »See all Psychopathology resources »