The effect of this inhibitor can be overcome with changes of [S] as teh inhibitor does not permanently alter/denature enzyme by staying attached, a non-covalent bond is formed.
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What does irreversible inhibitor mean?
Causes a change in active so so the enzyme can no longer form the correct bonds with the substrate.
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What effect does a competitive inhibitor have on Vmax and Km?
alter apparent km not Vmax, as Vmax can be reached but just at a higher [S] to overcome inhibitor.
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What effect does a non-competitive inhibitor have on Vmax and km?
Km is the same but V,ax is reduced because substrate conc can't overcome the inhibitor.
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What is a homotropic allosteric enzyme?
when substrate is the effector but binds somewhere else as well as the active site to produce or inhibit activity.
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Other cards in this set
Card 2
Front
What does irreversible inhibitor mean?
Back
Causes a change in active so so the enzyme can no longer form the correct bonds with the substrate.
Card 3
Front
What effect does a competitive inhibitor have on Vmax and Km?
Back
Card 4
Front
What effect does a non-competitive inhibitor have on Vmax and km?
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