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How does HIV affect our immune system?
We cannot deal with HIV - infection of the T helper CD4 cells - T cells kill virally infected cells and activate B cells > we actively destroy our T cells - progressively destroying immune response - CD4 cell count drops in HIV infection
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What are autoimmune diseases?
Diseases in which the immune system itself is responsible for creating the response resulting in host damage
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What is Coeliac Disease?
Gluten intolerance - autoimmune disease affecting small intestine - immune destruction of villi - leading to malabsorption - antibodies against TtGase
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What is Myasthenia Gravis?
Progressive disease - facial problems - immune destruction of acetylcholine receptors - damage to neuromuscular junction > lose muscle control - antibodies against acetylcholine receptor
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What are immune cancers?
Leukaemia: bone marrow/blood. Myeloma: bone marrow that effects plasma cells. Lymphoma: lymphatic system
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What is Acute Lymphoblastic Leukaemia?
Rapid increase of WBCs in body - cancer of lymphoid stem cell - anaemia, infection susceptebility, easy bruising, bone pain - either T or B cell overproduced - no space for other cells
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What is Multiple Myeloma
Cancer of plasma cell - B cells produced in bone marrow > move to lymph nodes > MM develops after an immune response > Become plasma cells > antibodies > loss of control of plasma cells - no space for other cells
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What is Hodgkin’s Lymphoma
Cancer of B cells in lymph nodes - swelling of lymph nodes - fever, fatigue, enlarged spleen - spreads node to node
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What is organ transplantation / rejection
An immune response to new tissue that it perceives as foreign - tissue becomes destroyed - antibodies are dissimilar
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What is immune suppression?
Reducing the effect of the immune system - preventing the body rejecting an organ transplant -
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Card 2

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What are autoimmune diseases?

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Diseases in which the immune system itself is responsible for creating the response resulting in host damage

Card 3

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What is Coeliac Disease?

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Card 4

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What is Myasthenia Gravis?

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Card 5

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What are immune cancers?

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