Electrophysiology IN VIVO

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  • Created by: molg
  • Created on: 19-05-18 16:28
EEG- electroencephalogram
electrodes placed on the skull- mostly measures summed synaptic excitation/inhibition on dendrites of cortical pyramidal neurons
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iEEG- intracranial EEG
placing electrodes on the surface of the brain
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ECoG-electrocorticography
type of iEEG- recording from the cortical surface using subdural electrodes/ grid electrodes
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local field potential (LFP)
is an electrophysiological signal generated by the summed electric current flowing from multiple nearby neurons within a small volume of nervous tissue
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sampling frequency in analog-digital (A/D) conversion
action potentials (duration 1ms or less) need to be sampled at much higher rates (~20KHz)
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Spectral (Fourier) analysis:
decomposing EEG signals into their constituent frequencies- which frequency is dominating
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Phase synchrony ("coherence")
infere cross-regional interactions- found less synchronous activity in frontal and parietal lobes in schizophrenia patients
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Depth electrodes
occurs in epileptic patients- locate seizures
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bandpass filtered signal
signal separated into individual frequency waves
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Spectrogram
- shows the power of the different frequencies at different time points
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Tetrodes
can discriminate between neuron activity- based on spacial information- place cell activity- can predict location of rat
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JUXTA recording- from single neurones
inject dye into active neuron- fixation purfuse tissue- immunohistochemistry
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Intracellular recording- from single electrode
impale neuron- can measure synaptic events with higher resolution
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Other cards in this set

Card 2

Front

placing electrodes on the surface of the brain

Back

iEEG- intracranial EEG

Card 3

Front

type of iEEG- recording from the cortical surface using subdural electrodes/ grid electrodes

Back

Preview of the back of card 3

Card 4

Front

is an electrophysiological signal generated by the summed electric current flowing from multiple nearby neurons within a small volume of nervous tissue

Back

Preview of the back of card 4

Card 5

Front

action potentials (duration 1ms or less) need to be sampled at much higher rates (~20KHz)

Back

Preview of the back of card 5
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