Drug effecting SNS

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What is inotropic?
Increase contraction of the heart
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What is chronotropic?
Increase heart rate.
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What drugs inhibit enzymes in synthetic pathway of NA/A?
A-methyl p-tyrosine blocks tyrosine hydroxylase. Cartidopa blocks dopa decarboxylase.
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Drugs that inhibit storage
Respirine blocks vascular transport
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Inhibition of release
Guanethidine blocks depolarisation-couple release of transmitter.
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How can NA/A be degraded?
By MAO monoamine oxidase.
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MAO inhibitors
prevent break down. but must not take tyrosine (in some old cheeses) while on it.
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What are sympathomimetics?
Drugs that cause NA to be release from adrenal medulla
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Drugs that displace storage
Amphetamine. Tyramine
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Drugs that inhibit reuptake
Cocaine, Imipramine.
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Card 2

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What is chronotropic?

Back

Increase heart rate.

Card 3

Front

What drugs inhibit enzymes in synthetic pathway of NA/A?

Back

Preview of the front of card 3

Card 4

Front

Drugs that inhibit storage

Back

Preview of the front of card 4

Card 5

Front

Inhibition of release

Back

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