Inhibit Na+/K+/Cl- reabsorption, meaning a fewer number of electrolytes remain in the limb lumen and hence a lesser volume of water is present in the lumen too
Inhibit Na+/K+/Cl- reabsorption, meaning a greater number of electrolytes remain in the limb lumen and hence a greater volume of water is present in the lumen
Inhibit Na+/K+/Cl- reabsorption, meaning a fewer number of electrolytes remain in the limb lumen and hence a greater volume of water is present in the lumen too
Inhibit Na+/K+/Cl- reabsorption, meaning a greater number of electrolytes remain in the limb lumen and hence a lesser volume of water is present in the lumen
7. Loop diuretics are commonly used in treating which of the following conditions?
Peripheral oedema, pulmonary oedema and congestive heart failure
Pulmonary oedema, hypertension and hypokalaemia
Peripheral oedema, angina pectoris and stroke
Pulmonary oedema, hypertension and diabetes
8. Symptomatic diuretic-induced gout can be treated by which of the following?
Mannitol
Allopurinol
Bumetanide
Calcitriol
9. Hyperuricaemia is a recognised adverse effect of thiazide diuretics. Why?
Thiazides promot excess uric acid reabsorption
Thiazides prevent uric acid reabsorption
Secretion of thiazides competes with uric acid secretion
Thiazides blow up uric acid
10. Broadly speaking, how do thiazide diuretics act?
Actively promote Na+/Cl- excretion
Actively promote Na+/Cl- reuptake
Inhibit Na+/Cl- reuptake
Inhibit Na+/Cl- excretion
11. Where do thiazide diuretics have their main action?
Loop of Henle
Distal convoluted tubule
Glomerulus
Proximal convoluted tubule
12. What is the mode of action of loop diuretics?
Inhibit Na+/K+/Cl- reabsorption, meaning a greater number of electrolytes remain in the limb lumen and hence a greater volume of water is present in the lumen
Inhibit Na+/K+/Cl- reabsorption, meaning a greater number of electrolytes remain in the limb lumen and hence a lesser volume of water is present in the lumen
Inhibit Na+/K+/Cl- reabsorption, meaning a fewer number of electrolytes remain in the limb lumen and hence a greater volume of water is present in the lumen too
Inhibit Na+/K+/Cl- reabsorption, meaning a fewer number of electrolytes remain in the limb lumen and hence a lesser volume of water is present in the lumen too
13. True or false: Spirinolactone's efficacy is enhanced in hyperaldosteronism?
True
False
14. Hyperuricaemia is a recognised adverse effect of thiazide diuretics. What can hyperuricaemia cause?
