Diuretic Drugs - BM5 RCR1

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1. Where do loop diuretics usually have their greatest action?

  • Thin ascending loop of Henle
  • Thick ascending loop of Henle
  • Thick descending loop of Henle
  • Thin descending loop of Henle
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2. What is the mode of action of loop diuretics?

  • Inhibit Na+/K+/Cl- reabsorption, meaning a fewer number of electrolytes remain in the limb lumen and hence a lesser volume of water is present in the lumen too
  • Inhibit Na+/K+/Cl- reabsorption, meaning a greater number of electrolytes remain in the limb lumen and hence a greater volume of water is present in the lumen
  • Inhibit Na+/K+/Cl- reabsorption, meaning a fewer number of electrolytes remain in the limb lumen and hence a greater volume of water is present in the lumen too
  • Inhibit Na+/K+/Cl- reabsorption, meaning a greater number of electrolytes remain in the limb lumen and hence a lesser volume of water is present in the lumen

3. Hypokalaemia is a recognised adverse effect of thiazide diuretics. What can this cause?

  • Cerebral haemorrhage
  • Arrythmias
  • Pneumonia
  • DVT

4. Loop diuretics are commonly used in treating which of the following conditions?

  • Pulmonary oedema, hypertension and diabetes
  • Pulmonary oedema, hypertension and hypokalaemia
  • Peripheral oedema, pulmonary oedema and congestive heart failure
  • Peripheral oedema, angina pectoris and stroke

5. True or false: loop diuretics are effective in situations where renal function is diminished?

  • True
  • False

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