Diagnostics

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Name some examples of CBC tests
WBC counts, RBC counts, Haemoglobin, Platelet counts, Mean platelet volume.
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What does a clinical biochemist/chemist do?
Detect and quantify substances that indicate damage or disease. Or detect toxic substances such as drugs.
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What specimens can be tested?
Whole blood, serum, plasma, Urine, CSF, ***** matter, hair sweat, amniotic fluid.
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What is measured?
Analytes
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Name some electrolytes and simple ions?
Na, K, Fe, Cl+ Ca Mg
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Name some small molecule analyses?
Glucose, Cholesterol, Urea, Creatinine, CO2, Bilirubin, Vitamins
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Name protein analytes?
Total protein, Albumin, Specific enzymes, immune system proteins, hormones
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What are chemical tests used for in diagnosis?
To either diagnose a problem or to shortlist which tests can help chose from
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Factors affecting prognosis?
Age, health, disease
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What can tests determine for prognosis?
Likely outcome of known disease state.
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High levels of PSA indicate?
Prostate cancer is malignant and likely to spread.
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What is screening?
Detection of disease at sub clinical levels, when symptoms have not been presented
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Screening tests must be?
Cheap and sensitive
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Name an example of how tests are used for monitoring?
Diabetic monitoring blood glucose levels.
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How can tests help with drug prescriptions?
Can be used to help prescribe correct drugs and amount needed, can also show toxic side effects and wether the drug will work or not.
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Where is ALP found? (Alkaline Phosphatase)
Liver, placenta, bone and intestine.
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ALP in plasma can be raised due to?
Bone disease, Hepatic conditions, Pregnancy.
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Increased AST plasma levels can indicate?
Liver problems, hepatitis, lower for chronic.
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CK increases by?
Heart attack, epilepsy, Skeletal muscle damage, severe exercise.
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If ALP Is high you will need further tests as....
This can indicate a lot of things.
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What is the chemical outcome of chronic pancreatitis?
Low serum levels of Ca, High glucose levels
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What would be detected chemically for acute pancreatitis?
High amylase, urea slightly high
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What would be detected on the test for Carcinoma in liver.
Bilirubin, GGT normal, albumin low.
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What would be detected on the test for Renal failure?
Urea, creatinine very high, haemoglobin low.
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Other cards in this set

Card 2

Front

What does a clinical biochemist/chemist do?

Back

Detect and quantify substances that indicate damage or disease. Or detect toxic substances such as drugs.

Card 3

Front

What specimens can be tested?

Back

Preview of the front of card 3

Card 4

Front

What is measured?

Back

Preview of the front of card 4

Card 5

Front

Name some electrolytes and simple ions?

Back

Preview of the front of card 5
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