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6. _____________ said diabetes is due to a deficiency of insulin, produced by the pancreas

  • Edward Albert Sharpey Schafer
  • Joseph von Mering and Oskar Minkowski
  • Egyptians

7. Antidiabetic agents are given at first then insulin injections in _______

  • Type 2
  • Type 1

8. Large urine output is ______

  • Polyphagia
  • Polyuria
  • Polydipsia

9. Around _______ loci contribute to type 1 diabetes

  • 5
  • 50
  • 20
  • 723

10. __________ has no c chain, and a and b chains are connected by disulphide bridges

  • Insulin
  • Preproinsulin
  • Proinsulin

11. __________ is caused by two defects: resistance to insulin as well as a deficiency in insulin secretion

  • Type 2 diabetes mellitus
  • Type 1 diabetes mellitus

12. Pancreatic acinar cells are

  • Exocrine
  • Endocrine

13. _______ promotes triglyceride storage in adipose tissue

  • Insulin
  • Glucagon

14. The more glucose in blood, the more glucose uptake via GLUT2 receptors on beta cells, the more ____________

  • Insulin release
  • Glucagon release

15. An increased acidity in the blood and other body tissue

  • Acidosis
  • Proteins
  • Ketosis
  • Uria

16. Glucose levels are regulated by insulin and glucagon, released by the endocrine __________

  • Pancreas
  • Liver

17. Diabetic retinopathy is ___________ microvascular complication of diabetes

  • Common
  • Rare

18. When cells can't take up glucose, they are 'starved', which leads to a symptom of ________

  • Anaemia
  • Polyphagia
  • Ketoacidosis

19. When insulin binds to its recetor on muscle cells, it causes a signal transduction which results in translocation of the glucose transporter GLUT 4 from __________

  • The inside of cells to the membrane
  • From the membrane to the inside of the cell

20. Type 1 diabetes is irreversible

  • True
  • False