Definitions Lecture 1 Introduction to MGG

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  • Created by: chandanee
  • Created on: 02-01-19 17:57
Gram +
Cytoplasmic membrane, Thick pep layer, polyalchols (teichoic acids), some covalently linked to lipoteichoic, purple stain
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Gram -
Cytoplasmic membrane, thin pep layer, bilayer, pink GS
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Peptidoglycan layer
Lattice structure formed from linear chain of alternating AA - NAG and NAM, B1, 4, glycosidic bond, covalent bridges, confer shape and mechanical protection
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Teichoic acids
Polyol phosphate polymers with a strong - charge, covalently linked to the pep layer in Gram+, strongly antigenic, absent in Gram-
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Lipoteichoic
Membrane polymers with glycophosphates and glycolipid and anchored in the cytoplasmic membrane
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LPS
major component of Gram -
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Cell envelope
surrounds the cytoplasm
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Cell membrane
phospholipid bilayer
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Glycoalyces
sticky external structures of cells that are loosely attached slime layers/capsules, prevents cells from drying out
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Capsules
protects cells from phagocytosis by other cells, made of high molecular weigh viscous polysaccharide gel and have slime layers
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Fimbriae/Pili
sticky bristle-like projections, adhere cells and environmental surfaces. Hollow, non-motile tubes, adhesion, sex pili distinguished by their ability to bind to male bacteriophages and attach. Also, to RBC - colonisation
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Flagella
Move to conditions, Filament hook and basal body, polar/petrichous, propels cells, counter-clockwise rotation, proton motive force, chemotaxis
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Flagellins
immunogenic, contain H antigens
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Chromosome
circular, dsdna, supercoiling
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Plasma membrane
3:1 protein to phospholipid, transport biosynthesis and energy transduction
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Bacterial morphology
binary fission, single celled, lack a nuclear membrane, use HC substrates, adapt to changing environments, advances led to vaccines
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Viruses
Do not divide/grow independently, obligate intracellular parasites, contain DNA/RNA, cannot generate ATP, acellular, enzymatic, MGE
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Classification of Virus
Nucleic acid content, capsid symmetry, presence/absence of envelope, size replication strategy, virion, nucleocapsid
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Virus morphology
Helical = helical arrays of capsid proteins (protomers) wrapped around helical filament of NA. Icosahedral (spherical) no and arrangement of capsomeres used in ID. Replication: DNA/RNA, **/ds/linear/circular
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Structure/function of virus
Deliver its genome into the HC
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Other cards in this set

Card 2

Front

Cytoplasmic membrane, thin pep layer, bilayer, pink GS

Back

Gram -

Card 3

Front

Lattice structure formed from linear chain of alternating AA - NAG and NAM, B1, 4, glycosidic bond, covalent bridges, confer shape and mechanical protection

Back

Preview of the back of card 3

Card 4

Front

Polyol phosphate polymers with a strong - charge, covalently linked to the pep layer in Gram+, strongly antigenic, absent in Gram-

Back

Preview of the back of card 4

Card 5

Front

Membrane polymers with glycophosphates and glycolipid and anchored in the cytoplasmic membrane

Back

Preview of the back of card 5
View more cards

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