CMB 1001 Immunology Complement and the Classical pathway

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Created by: Chris mc
Created on: 10-04-11 14:25

An activated C1q contains at least 2 globular heads and a constant region of an antibody?

True

1 of 13

C1s generates an enzyme. Which enzyme does it make?

Serine protease

2 of 13

C1s cleaves? to Cnumber a and b

3 of 13

What is the Classical pathway C3 convertase?

C4b2b

4 of 13

C3b contains a.....?

thioester bond

5 of 13

MAC stands for Membrane Attack Compound?

False

6 of 13

What binds to the pathogen surface?

C5b

7 of 13

C8 is comprised of C8beta (A) and C8 alpha- gamma (B). Which inserts into the lipid bilayer?

8 of 13

C1q molecules have 7 globular heads and a common stem?

False

9 of 13

...Allows polymerisation of 10 to 16 molecules of C9 thus forming the ring structure?

10 of 13

The MAC complex comprises C5b6789 ?

True

11 of 13

....Binds to C5b?

12 of 13

The classical pathway involves?

Antigen/ antibody complexes

13 of 13

Other cards in this set

Card 2

Front

C1s generates an enzyme. Which enzyme does it make?

Back

Serine protease

Card 3

Front

C1s cleaves? to Cnumber a and b

Back

Card 4

Front

What is the Classical pathway C3 convertase?

Back

Card 5

Front

C3b contains a.....?

Back

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CMB 1001 Immunology Complement and the Classical pathway