Clinical biochem- hormones

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  • Created by: Lou
  • Created on: 20-04-17 13:47
which hormones are produced by the thyroid gland?
thyroxine (T4), triiodothyronine (T3) and calcitonin
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What are the two major types of endocrine disorder?
Hypofunction and hyperfunction
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In primary hyperthyroidism, would you expect a raised or lowered TSH?
lowered (due to -ve feedback of thyroxine (T4)
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What is meant by an ectopic hormone?
hormones produced by tumours derived from tissues that are not normally engaged in the production of that hormone
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What connects the 2 lobes in the thyroid gland?
isthmus
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What is TRH?
thyrotropin-releasing hormone
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What is TSH?
thyroid-stimulating hormone
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What is the usual cause of primary hyperthyroidism?
problem with thyroid gland; excessive hormone production
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What is the usual cause of secondary hyperthyroidism?
a tumour in the pituitary gland
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What is Graves disease and what does it cause?
autoimmune- antibodies bind to TSH receptors and chronically stimulate them- T3 and T4 levels elevated
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What is Hashimoto's disease and what does it cause?
autoimmune- thyroid is gradually being destroyed, loss of hormone synthesis
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Which plasma proteins are involved in transporting thyroid hormones?
Thyroid-binding globulin, pre-albumin and albumin
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Which thyroid hormone is active at the cellular level?
Triiodothyronine (T3)
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Most modern labs measure which hormones in their thyroid screen?
Free T4 and TSH
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Other cards in this set

Card 2

Front

What are the two major types of endocrine disorder?

Back

Hypofunction and hyperfunction

Card 3

Front

In primary hyperthyroidism, would you expect a raised or lowered TSH?

Back

Preview of the front of card 3

Card 4

Front

What is meant by an ectopic hormone?

Back

Preview of the front of card 4

Card 5

Front

What connects the 2 lobes in the thyroid gland?

Back

Preview of the front of card 5
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