Clinical biochem- Enzymology

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  • Created by: Lou
  • Created on: 20-04-17 15:18
what is meant by an 'isoenzyme' ?
Enzymes that differ in structure/ sequence, but perform the same function/ catalyse the same reaction
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what is an enzyme isoform?
A post transnational modification of the enzyme
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What is a biomarker?
a naturally occurring molecule by which a particular disease can be identified
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what intracellular enzymes are lost through a leaky membrane?
cytosolic enzymes
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What are the main isoenzymes of creatine kinase?
CK-MM, CK-MB and CK-BB
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Which enzyme is useful for monitoring alcoholics?
y-glutamyltransferase (GGT)
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Following a myocardial infarction, which enzyme becomes elevated in the blood first?
creatine kinase
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Is AST a marker of hepatic or cholestatic disease?
hepatic disease
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How many isoenzymes does lactate dehydrogenase (LDH) have?
5
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At what pH does alkaline phosphate perform with maximum activity?
pH 9-10
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What enzyme is increased in acute pancreatitis?
amylase
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Card 2

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what is an enzyme isoform?

Back

A post transnational modification of the enzyme

Card 3

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What is a biomarker?

Back

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Card 4

Front

what intracellular enzymes are lost through a leaky membrane?

Back

Preview of the front of card 4

Card 5

Front

What are the main isoenzymes of creatine kinase?

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