Less risk of undesirable side efects, drug doses are reduced.
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Three ways to produce a single-isomer during synthesis?
Enzymes (which are stereo-specific), chiral pool synthesis, transition element complexes.
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Advantages of chirality in Ibuprofen?
Non-active isomer is converted to active form int he body, 1/2 dose required as both isomers are effective, cheaper and quicker to produce as no separation required.
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Define Chirality
A molecule which produces non-superimposable mirror images of itself.
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Define Chiral Carbon.
C attached to 4 DIFFERENT variable groups (R).
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Other cards in this set
Card 2
Front
Three ways to produce a single-isomer during synthesis?
Back
Enzymes (which are stereo-specific), chiral pool synthesis, transition element complexes.
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