Chemistry 3

What is pH?
A measure of free hydrogen ions, not those bound to anions.
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What is the blood pH?
7.35-7.45
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Where is most acids in the body produced?
By the breakdown of proteins, incomplete oxidation of fats or glucose.
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What is the pH where weak acid/bases is the buffer?
When it is 50% associated and 50% dissociated. On a graph when the line is flat it is buffering.
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Define pH
pH= pKa+log(conjugate base/acid). when equal associated and dissociation pH=pKa
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What acid is the buffer in urine?
phosphoric acid.
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What is the only aa that acts a buffer?
Histidine as it has a pKa side chain of 6. Only acidic and basic ones have potential to be buffers.
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Why is haemoglobin a good buffer?
It has lots of histidine. oxyhaem pKa 6.8 deoxyhaem 7.8. deoxy is a better buffer for H+ produced in metabolism.
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Other cards in this set

Card 2

Front

What is the blood pH?

Back

7.35-7.45

Card 3

Front

Where is most acids in the body produced?

Back

Preview of the front of card 3

Card 4

Front

What is the pH where weak acid/bases is the buffer?

Back

Preview of the front of card 4

Card 5

Front

Define pH

Back

Preview of the front of card 5
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