Chapter 11 The Cell Cylcle

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  • Created by: Kate
  • Created on: 17-02-14 14:29
What is the function of DNA Helicase?
It is a catabolic enzyme that breaks the hydrogen bonds between base pairs so that DNA replication can occur
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What is the function of DNA Polymerase?
It is an anabolic enzyme which joins free activated nucleotides to the original strands of DNA during DNA replication
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How do the two separated strands of DNA act as templates?
The two strands acts as bases. Free activated nucleotides which are complementary to the original bases (on the strand of DNA) combine, this results in two identical strands of DNA (as each strands retains half the original DNA material)
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What is semi-conservative replication?
The process/method in which DNA replicates, resulting in the two new strands having half of the original DNA material
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What are the outcomes of Mitosis?
2 Identical Cloned Daughter Cells
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Describe what happens during Interphase (of Mitosis)
Normal cellular activities. DNA Replication.
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Describe what happens during Prophase (of Mitosis)
Chromosomes condense and become visible. Nucleolus fades. Centriole duplicates and begins to move towards poles - spindle begins to form
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Describe what happens during Metaphase (of Mitosis)
Sister Chromatids line up on the equator. Microtubules of Spindle (now completely formed) attach to centromere of sister chromatids. Nuclear envelope breaks down.
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Describe what happens during Anaphase (of Mitosis)
Microtubules of spindle pull sister chromatids apart from centromere towards opposite poles.
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Describe what happens during Telophase (of Mitosis)
Chromosomes reach opposite poles and de-condense. Nuclear envelope and nucleolus reforms. Cytocinesis occurs.
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State three reasons why Mitosis is important
Growth, Repair and Differentiation
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What are the three stages of The Cell Cycle?
Interphase, Nuclear Division, Cell Division
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What is the longest stage of Mitosis?
Interphase
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How do drugs (eg. Chemotherapy) treat cancer?
They disrupt the cell cycle by preventing DNA from replicating, and inhibits metaphase stage by interfering with spindle formation
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What is Cancer?
Cancer is the uncontrolled growth of cells that results in the development of a tumour. It is a result of damage to genes that regulate mitosis and the cell cycle.
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What is the function of DNA Polymerase?

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It is an anabolic enzyme which joins free activated nucleotides to the original strands of DNA during DNA replication

Card 3

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How do the two separated strands of DNA act as templates?

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Card 4

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What is semi-conservative replication?

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Card 5

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What are the outcomes of Mitosis?

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