1) cancer biomarkers/therapies 2) biomimetic membranes 3) as drug targets for diseases they are implicated in
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How are they being used in biomimetic membranes?
To purify/desalinate water
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What is difficult about it?
To make them strong and stable enough to withstand operating pressures & repeated cleaning
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What is the key to overcome this issue? (and according to who?)
use an appropriately matched AQP to the membrane material, which would allow scalability & durability (according to Danfoss AquaZ- a Danish company)
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Why can they be used as biomarkers for cancer?
They are expressed in over 20 human cancer types, and their expression significantly correlates with the severity of histological tumours
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Why might they also be useful in the treatment of cancers?
recent evidence shows AQPs could play a role in tumour-associated edema as well as tumour cell proliferation & migration (hence inhibitors could be a therapeutic strategy)
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Other cards in this set
Card 2
Front
How are they being used in biomimetic membranes?
Back
To purify/desalinate water
Card 3
Front
What is difficult about it?
Back
Card 4
Front
What is the key to overcome this issue? (and according to who?)
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