Cell Biology: The Cytoskleton

?
  • Created by: KayshaN
  • Created on: 22-10-19 11:10
The cytoskleton is....
Dynamic, chnages constantly
1 of 14
What are the general functions of the cytoskelton?
Keeps Shape, llows Cell Movement (Locomation), Mediates intracellular movement.
2 of 14
What are the fucntions of Actin Filaments?
cell movements, provide force
3 of 14
What are the functions of Microfilaments?
cell organsiation, cell movement, transport network
4 of 14
What are the functions of Intermediate Filaments?
strength, protection, specialised struture, sit around nucleus
5 of 14
What is the diameter of Actin, Microtubules and Intermediate Filaments?
1) 7nm 2) 25nm 3)8-12nm
6 of 14
Outline the struture of Actin.
Monomers are G-actin (globular) and Polymers are F-actin (fiberous). Have plus end and kinus end, stick together oposites. Can bind to ATP InG-actin not much happening, but F-actin more hydrolysis means less stable
7 of 14
How does Actin cause cell movement?
With help other proteins, polymersiation and depolymerisation, can dissasemble and reassemble to chage direction or cell.
8 of 14
What key process are Actin Filaments vital in?
Cell division, cytokineses, contractile ring to seperate daughter cells.
9 of 14
Ouline the structure of Microtubules.
alpha-beta-tubulin dimers. One end plus, other minus. Interact laterally, created hollow barrel structure. Bind to GTP, helps regulate stability, when in filaments more breakdown GTP-GDP, kink in filament unstable
10 of 14
What is Microfilaments role in Intracellular Transport?
motor protiens use microtubules as a network to move vesicles and organelles, travel in different directions depeding of polarity.
11 of 14
How is Chemotherapy related to the cytoskeleton?
Actin Filaments and Microtubules are a target for this, Taxol stabilses MT and stops mitosis, treatment of ovarian caricinmoers etc.
12 of 14
Outline the structure of Intermediate Filaments.
Have helical domains at head and tail, associate with one another creating dimers antiparrel fashion, Less dynamic, can form specialist strutures e.g. nuclear envolope , Keratins
13 of 14
How are INtermediate Filaments involved in Skin Conditions?
Mutations in intermediate filament genes, disrupt Keratin, dont have enough Keratin, touch skin and will fall off, no strength
14 of 14

Other cards in this set

Card 2

Front

What are the general functions of the cytoskelton?

Back

Keeps Shape, llows Cell Movement (Locomation), Mediates intracellular movement.

Card 3

Front

What are the fucntions of Actin Filaments?

Back

Preview of the front of card 3

Card 4

Front

What are the functions of Microfilaments?

Back

Preview of the front of card 4

Card 5

Front

What are the functions of Intermediate Filaments?

Back

Preview of the front of card 5
View more cards

Comments

No comments have yet been made

Similar Human Biology resources:

See all Human Biology resources »See all The Cytoskleton resources »