Cell biology 9S.1 0.0 / 5 ? BiologyPrinciples of cell communicationUniversityAll boards Created by: Jasmine FinchCreated on: 24-05-20 18:29 extracellular signals molecules are recieved by a receptor protein 1 of 20 intracellular signalling proteins process the signal and distribute it to the appropriate effors 2 of 20 What are the 4 types of inter-cellular signalling? contact-dependant, paracrine, synaptic and endocrine 3 of 20 what are two extracellular molecules? nitric oxide and insulin 4 of 20 examples of lipophilic hormones cortisol, estradiol, thyroxine etc 5 of 20 what binds to the receptor preventing DNA binding and gene transcription? inhibitory protein 6 of 20 What binds to allow transcription ligand 7 of 20 how do ligands bind to proteins? by noncovalent interactions 8 of 20 the occupancy of the receptor is... proportional to the concentration of the ligand 9 of 20 What are the three classes of cell surface receptors? ion channel coupled, G protein coupled and enzyme coupled 10 of 20 what are exampled of intracellular signalling proteins c-AMP, diacylglycerol (often called second messengers) 11 of 20 what is cAMP? a small molecule involved in the trasmission of certain signals inside cells 12 of 20 what three types of amino acids do phosphate attach to side chains? serine, threonine and tyrosine 13 of 20 Cytokines immune messenger molecule often acting at short distances 14 of 20 SH2 domain a recurring protein domain in intracellular signalling 15 of 20 What does the binding of GTP do? changes the conformation of the G protein, enabling it to transmit signals 16 of 20 what additional proteins does GTP rely on? GAP and GEF 17 of 20 what does the Wnt pathway regulate? proliferation in the small intestine 18 of 20 Growth signals from Wnt proteins are submitted when.. b-catenin accumulates 19 of 20 What is a molecular switch? A molecule or an event able to switch on or off a signalling pathway 20 of 20
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